Zafirlukast is used by patients with mild-to-moderate asthma to decrease the symptoms of asthma and the number of acute asthma attacks. It is not a "rescue" medicine.
Zileuton is an orally active inhibitor of 5-lipoxygenase, the enzyme that catalyzes the formation of leukotrienes from arachidonic acid. It is indicated for the prophylaxis and chronic treatment of asthma in adults and children 12 years of age and older.
Zoledronic acid is an intravenous (IV) bisphosphonate for the treatment of hypercalcemia of malignancy (HCM) providing a higher response rate compared to pamidronate disodium.